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Term Information

Accession
GO:0005391
Name
P-type sodium:potassium-exchanging transporter activity
Ontology
molecular_function
Synonyms
P-type sodium:potassium-exchanging ATPase activity, sodium/potassium-exchanging ATPase activity, sodium/potassium-transporting ATPase activity, sodium:potassium exchanging ATPase activity, sodium:potassium-exchanging ATPase activity, Na(+)/K(+)-ATPase activity, Na(+)/K(+)-exchanging ATPase activity, Na+,K+-ATPase activity, Na+/K+-ATPase activity, Na+/K+-exchanging ATPase activity, Na,K-activated ATPase activity, sodium pump
Alternate IDs
None
Definition
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) + K+(out) = ADP + phosphate + Na+(out) + K+(in). Source: EC:7.2.2.13
Comment
None
History
See term history for GO:0005391 at QuickGO
Subset
None
Feedback
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Parents of P-type sodium:potassium-exchanging transporter activity (GO:0005391)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
P-type sodium:potassium-exchanging transporter activity [is_a relation] is_a  P-type sodium transporter activity (GO:0008554)
P-type sodium:potassium-exchanging transporter activity [is_a relation] is_a  P-type potassium transmembrane transporter activity (GO:0008556)
P-type sodium:potassium-exchanging transporter activity [BFO:0000050 relation] BFO:0000050  establishment or maintenance of transmembrane electrochemical gradient (GO:0010248)
Children of P-type sodium:potassium-exchanging transporter activity (GO:0005391)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
positive regulation of P-type sodium:potassium-exchanging transporter activity (GO:1903408) [RO:0002213 relation] RO:0002213  P-type sodium:potassium-exchanging transporter activity
regulation of P-type sodium:potassium-exchanging transporter activity (GO:1903406) [RO:0002211 relation] RO:0002211  P-type sodium:potassium-exchanging transporter activity
P-type sodium:potassium-exchanging transporter activity involved in regulation of cardiac muscle cell membrane potential (GO:0086037) [is_a relation] is_a  P-type sodium:potassium-exchanging transporter activity
negative regulation of P-type sodium:potassium-exchanging transporter activity (GO:1903407) [RO:0002212 relation] RO:0002212  P-type sodium:potassium-exchanging transporter activity
EC
7.2.2.13
MetaCyc
3.6.3.9-RXN
Reactome
R-HSA-936897
RHEA
18353
TC
3.A.3.1.1