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asialoglycoprotein receptor activity
Term Information
Accession
GO:0004873
Name
asialoglycoprotein receptor activity
Ontology
molecular_function
Synonyms
None
Alternate IDs
None
Definition
Receiving an asialoglycoprotein, and delivering the asialoglycoprotein into the cell via endocytosis. An asialoglycoprotein is a plasma glycoproteins from which the terminal sialic acid residue on their complex carbohydrate groups has been removed. The asialoglycoprotein receptor recognizes the terminal galactose and N-acetylgalactosamine units of the asialoglycoprotein, the receptor-ligand complex is internalized and transported to a sorting organelle where disassociation occurs before the receptor is recycled to the cell membrane.
Source:PMID:11278827,
PMID:7624395,
GOC:bf,
Wikipedia:Asialoglycoprotein
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