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Term Information

Accession
GO:0004623
Name
phospholipase A2 activity
Ontology
molecular_function
Synonyms
lecithinase A activity, phosphatidase activity, phosphatidolipase activity, phosphatidylcholine 2-acylhydrolase activity, cytosolic phospholipase A2 activity, phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine), phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine), secreted phospholipase A2 activity
Alternate IDs
GO:0102568, GO:0102567
Definition
Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phospholipid + H2O = 1-acyl-sn-glycero-3-phospholipid + a fatty acid. This reaction removes the fatty acid attached to the sn2-position. Substrates include phosphatidylcholine, phosphatidylethanolamine, choline plasmalogen and phosphatides. Source: RHEA:15801
Comment
None
History
See term history for GO:0004623 at QuickGO
Subset
goslim_chembl
Feedback
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Parents of phospholipase A2 activity (GO:0004623)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
phospholipase A2 activity [is_a relation] is_a  phospholipase activity (GO:0004620)
phospholipase A2 activity [is_a relation] is_a  carboxylic ester hydrolase activity (GO:0052689)
Children of phospholipase A2 activity (GO:0004623)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of phospholipase A2 activity (GO:1900138) [RO:0002212 relation] RO:0002212  phospholipase A2 activity
calcium-dependent phospholipase A2 activity (GO:0047498) [is_a relation] is_a  phospholipase A2 activity
positive regulation of phospholipase A2 activity (GO:0032430) [RO:0002213 relation] RO:0002213  phospholipase A2 activity
regulation of phospholipase A2 activity (GO:0032429) [RO:0002211 relation] RO:0002211  phospholipase A2 activity
calcium-independent phospholipase A2 activity (GO:0047499) [is_a relation] is_a  phospholipase A2 activity