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Term Information

Accession
GO:0004509
Name
steroid 21-monooxygenase activity
Ontology
molecular_function
Synonyms
steroid 21-hydroxylase activity, 21-hydroxylase activity, steroid,hydrogen-donor:oxygen oxidoreductase (21-hydroxylating), cytochrome P450 CYP21A1, cytochrome p450 XXIA1 activity
Alternate IDs
None
Definition
Catalysis of the reaction: A C(21) steroid + [reduced NADPH--hemoprotein reductase] + O2 = a 21-hydroxy-C(21)-steroid + [oxidized NADPH--hemoprotein reductase] + H2O. Source: RHEA:65612
Comment
None
History
See term history for GO:0004509 at QuickGO
Subset
None
Feedback
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Parents of steroid 21-monooxygenase activity (GO:0004509)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
steroid 21-monooxygenase activity [is_a relation] is_a  steroid hydroxylase activity (GO:0008395)
steroid 21-monooxygenase activity [is_a relation] is_a  oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705)
Children of steroid 21-monooxygenase activity (GO:0004509)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
progesterone 21-hydroxylase activity (GO:0106309) [is_a relation] is_a  steroid 21-monooxygenase activity
17-hydroxyprogesterone 21-hydroxylase activity (GO:0103069) [is_a relation] is_a  steroid 21-monooxygenase activity