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Term Information

Accession
GO:0004500
Name
dopamine beta-monooxygenase activity
Ontology
molecular_function
Synonyms
dopamine b-hydroxylase activity, (3,4-dihydroxyphenethylamine)beta-mono-oxygenase activity, 3,4-dihydroxyphenethylamine beta-oxidase activity, 3,4-dihydroxyphenethylamine,ascorbate:oxygen oxidoreductase (beta-hydroxylating), 4-(2-aminoethyl)pyrocatechol beta-oxidase activity, MDBH (membrane-associated dopamine beta-monooxygenase), SDBH (soluble dopamine beta-monooxygenase), dopa beta-hydroxylase activity, dopamine beta-hydroxylase activity, dopamine beta-oxidase activity, dopamine hydroxylase activity, dopamine-B-hydroxylase activity, oxygenase, dopamine beta-mono-, phenylamine beta-hydroxylase activity
Alternate IDs
None
Definition
Catalysis of the reaction: L-ascorbate + dopamine + O2 = (R)-noradrenaline + dehydroascorbate + H2O. Source: EC:1.14.17.1, RHEA:19117
Comment
None
History
See term history for GO:0004500 at QuickGO
Subset
None
Feedback
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Parents of dopamine beta-monooxygenase activity (GO:0004500)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
dopamine beta-monooxygenase activity [is_a relation] is_a  oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen (GO:0016715)

This term has no children.

EC
1.14.17.1
KEGG_REACTION
R02535
MetaCyc
DOPAMINE-BETA-MONOOXYGENASE-RXN
Reactome
R-HSA-209891
RHEA
19117