Planteome: Term Details for "calcidiol 1-monooxygenase activity" (GO:0004498)

You are using the Cyverse mirror of the Planteome Ontology Browser. The main site is currently down for maintenance.

Notice

Some functionality on this page depends on JavaScript. To fully use the features of AmiGO 2, enable JavaScript in your browser and reload from the landing page.

Term Information

Accession: GO:0004498
Name: calcidiol 1-monooxygenase activity
Ontology: molecular_function
Synonyms: 25-hydroxy vitamin D3 1-alpha-hydroxylase activity, 25-hydroxycholecalciferol 1-hydroxylase activity, calcidiol,NADPH:oxygen oxidoreductase (1-hydroxylating), 1-hydroxylase-25-hydroxyvitamin D3 activity, 25-OHD-1 alpha-hydroxylase activity, 25-hydroxy D3-1alpha-hydroxylase activity, 25-hydroxycholecalciferol 1-monooxygenase activity, 25-hydroxycholecalciferol 1alpha-hydroxylase activity, 25-hydroxycholecalciferol-1-hydroxylase activity, 25-hydroxyvitamin D-1 alpha hydroxylase activity, 25-hydroxyvitamin D3 1alpha-hydroxylase activity, cytochrome P450 CYP27B
Alternate IDs: None
Definition: Catalysis of the reaction: calcidiol + H+ + NADPH + O2 = calcitriol + H2O + NADP+. Source: RHEA:20573, EC:1.14.15.18
Comment: None
History: See term history for GO:0004498 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to calcidiol 1-monooxygenase activity.; Link to all direct and indirect annotations to calcidiol 1-monooxygenase activity.; Link to all direct and indirect annotations download (limited to first 10,000) for calcidiol 1-monooxygenase activity.
Feedback: Contact the Planteome feedback if you find mistakes or have concerns about the data you find here.
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

Filter results

Viewing options

BFO:0000001 entity
BFO:0000003 occurrent
BFO:0000015 process
GO:0008150 biological_process
GO:0009987 cellular process
GO:0008152 metabolic process
GO:0009058 biosynthetic process
GO:0044237 cellular metabolic process
GO:0071704 organic substance metabolic process
GO:0044238 primary metabolic process
GO:0044281 small molecule metabolic process
GO:0044249 cellular biosynthetic process
GO:0006629 lipid metabolic process
GO:0003674 molecular_function
GO:1901360 organic cyclic compound metabolic process
GO:1901615 organic hydroxy compound metabolic process
GO:1901576 organic substance biosynthetic process
GO:0044283 small molecule biosynthetic process
GO:0006766 vitamin metabolic process
GO:0006066 alcohol metabolic process
GO:0003824 catalytic activity
GO:0006775 fat-soluble vitamin metabolic process
GO:0008610 lipid biosynthetic process
GO:1901362 organic cyclic compound biosynthetic process
GO:1901617 organic hydroxy compound biosynthetic process
GO:0008202 steroid metabolic process
GO:0009110 vitamin biosynthetic process
GO:0046165 alcohol biosynthetic process
GO:0042362 fat-soluble vitamin biosynthetic process
GO:0016491 oxidoreductase activity
GO:0019751 polyol metabolic process
GO:1902652 secondary alcohol metabolic process
GO:0006694 steroid biosynthetic process
GO:0042359 vitamin D metabolic process
GO:0004497 monooxygenase activity
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0046173 polyol biosynthetic process
GO:0042368 vitamin D biosynthetic process
GO:0070640 vitamin D3 metabolic process
GO:0036378 calcitriol biosynthetic process from calciol
GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
GO:0004498 calcidiol 1-monooxygenase activity
GO:0010956 negative regulation of calcidiol 1-monooxygenase activity
GO:0060559 positive regulation of calcidiol 1-monooxygenase activity
GO:0060558 regulation of calcidiol 1-monooxygenase activity

Parents of calcidiol 1-monooxygenase activity (GO:0004498)

subject	relation	object
calcidiol 1-monooxygenase activity	BFO:0000050	calcitriol biosynthetic process from calciol (GO:0036378)
calcidiol 1-monooxygenase activity	is_a	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen (GO:0016709)

Children of calcidiol 1-monooxygenase activity (GO:0004498)

subject	relation	object
negative regulation of calcidiol 1-monooxygenase activity (GO:0010956)	RO:0002212	calcidiol 1-monooxygenase activity
positive regulation of calcidiol 1-monooxygenase activity (GO:0060559)	RO:0002213	calcidiol 1-monooxygenase activity
regulation of calcidiol 1-monooxygenase activity (GO:0060558)	RO:0002211	calcidiol 1-monooxygenase activity

EC: 1.14.15.18
KEGG_REACTION: R03610
MetaCyc: CALCIDIOL-1-MONOOXYGENASE-RXN
Reactome: R-HSA-209868; R-HSA-5602186
RHEA: 20573