Planteome: Term Details for "helicase activity" (GO:0004386)

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Term Information

Accession: GO:0004386
Name: helicase activity
Ontology: molecular_function
Synonyms: ATP-dependent helicase activity
Alternate IDs: GO:0008026
Definition: Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA or RNA helix. Source: GOC:jl
Comment: Note that most helicases catalyze processive duplex unwinding.
History: See term history for GO:0004386 at QuickGO
Subset: goslim_chembl; goslim_yeast; goslim_candida; goslim_pir
Related: Link to all annotated objects annotated to helicase activity.; Link to all direct and indirect annotations to helicase activity.; Link to all direct and indirect annotations download (limited to first 10,000) for helicase activity.
Feedback: Contact the Planteome feedback if you find mistakes or have concerns about the data you find here.
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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BFO:0000001 entity
BFO:0000003 occurrent
BFO:0000015 process
GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0140657 ATP-dependent activity
GO:0140640 catalytic activity, acting on a nucleic acid
GO:0004386 helicase activity
GO:0003678 DNA helicase activity
GO:0033677 DNA/RNA helicase activity
GO:0051097 negative regulation of helicase activity
GO:0051096 positive regulation of helicase activity
GO:0051095 regulation of helicase activity
GO:0003724 RNA helicase activity

Parents of helicase activity (GO:0004386)

subject	relation	object
helicase activity	is_a	catalytic activity, acting on a nucleic acid (GO:0140640)
helicase activity	is_a	ATP-dependent activity (GO:0140657)

Children of helicase activity (GO:0004386)

subject	relation	object
regulation of helicase activity (GO:0051095)	RO:0002211	helicase activity
negative regulation of helicase activity (GO:0051097)	RO:0002212	helicase activity
DNA/RNA helicase activity (GO:0033677)	is_a	helicase activity
RNA helicase activity (GO:0003724)	is_a	helicase activity
DNA helicase activity (GO:0003678)	is_a	helicase activity
positive regulation of helicase activity (GO:0051096)	RO:0002213	helicase activity

Reactome: R-HSA-5690996; R-HSA-169461; R-HSA-5686410; R-HSA-169468