Planteome: Term Details for "cysteine-type endopeptidase activity" (GO:0004197)

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Term Information

Accession: GO:0004197
Name: cysteine-type endopeptidase activity
Ontology: molecular_function
Synonyms: thiol endopeptidase activity, caspase activity, lysosomal cysteine-type endopeptidase, metacaspase activity
Alternate IDs: None
Definition: Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile. Source: https://www.ebi.ac.uk/merops/about/glossary.shtml#ENDOPEPTIDASE, https://www.ebi.ac.uk/merops/about/glossary.shtml#CATTYPE, GOC:mah
Comment: None
History: See term history for GO:0004197 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to cysteine-type endopeptidase activity.; Link to all direct and indirect annotations to cysteine-type endopeptidase activity.; Link to all direct and indirect annotations download (limited to first 10,000) for cysteine-type endopeptidase activity.
Feedback: Contact the Planteome feedback if you find mistakes or have concerns about the data you find here.
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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BFO:0000001 entity
BFO:0000003 occurrent
BFO:0000015 process
GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0140096 catalytic activity, acting on a protein
GO:0016787 hydrolase activity
GO:0008233 peptidase activity
GO:0008234 cysteine-type peptidase activity
GO:0004175 endopeptidase activity
GO:0004197 cysteine-type endopeptidase activity
GO:0004198 calcium-dependent cysteine-type endopeptidase activity
GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process
GO:0003923 GPI-anchor transamidase activity
GO:2000117 negative regulation of cysteine-type endopeptidase activity
GO:2001056 positive regulation of cysteine-type endopeptidase activity
GO:2000116 regulation of cysteine-type endopeptidase activity
GO:0070137 ubiquitin-like protein-specific endopeptidase activity

Parents of cysteine-type endopeptidase activity (GO:0004197)

subject	relation	object
cysteine-type endopeptidase activity	is_a	endopeptidase activity (GO:0004175)
cysteine-type endopeptidase activity	is_a	cysteine-type peptidase activity (GO:0008234)

Children of cysteine-type endopeptidase activity (GO:0004197)

subject	relation	object
negative regulation of cysteine-type endopeptidase activity (GO:2000117)	RO:0002212	cysteine-type endopeptidase activity
calcium-dependent cysteine-type endopeptidase activity (GO:0004198)	is_a	cysteine-type endopeptidase activity
cysteine-type endopeptidase activity involved in apoptotic process (GO:0097153)	is_a	cysteine-type endopeptidase activity
GPI-anchor transamidase activity (GO:0003923)	is_a	cysteine-type endopeptidase activity
positive regulation of cysteine-type endopeptidase activity (GO:2001056)	RO:0002213	cysteine-type endopeptidase activity
regulation of cysteine-type endopeptidase activity (GO:2000116)	RO:0002211	cysteine-type endopeptidase activity
ubiquitin-like protein-specific endopeptidase activity (GO:0070137)	is_a	cysteine-type endopeptidase activity

EC: 3.4.22.-
Reactome: R-HSA-9694601; R-HSA-5357828; R-HSA-211190; R-HSA-9697750; R-HSA-9684321; R-HSA-1236948; R-HSA-9647999; R-HSA-9694441; R-HSA-9013895; R-HSA-264865; R-HSA-201637; R-HSA-9729730; R-HSA-202967; R-HSA-201636; R-HSA-9647680; R-HSA-201639; R-HSA-202969; R-HSA-2028697; R-HSA-351901; R-HSA-202960; R-HSA-418846; R-HSA-201595; R-HSA-418845; R-HSA-201631; R-HSA-201630; R-HSA-2028692; R-HSA-202966; R-HSA-350651; R-HSA-201634; R-HSA-9012556; R-HSA-114261; R-HSA-2130706; R-HSA-933532; R-HSA-211186; R-HSA-9684352; R-HSA-9684351; R-HSA-351849; R-HSA-9694551; R-HSA-5682377; R-HSA-9686930; R-HSA-2130504; R-HSA-2130349; R-HSA-201628; R-HSA-1678920; R-HSA-202917; R-HSA-201629; R-HSA-9647632; R-HSA-351936; R-HSA-212552; R-HSA-139952; R-HSA-201622; R-HSA-351894; R-HSA-352268; R-HSA-9694625; R-HSA-114252; R-HSA-9684309; R-HSA-9684340; R-HSA-9729704; R-HSA-5634228; R-HSA-9603534; R-HSA-5660663; R-HSA-2130336; R-HSA-350158; R-HSA-202947; R-HSA-9710101; R-HSA-9684273; R-HSA-350319; R-HSA-350318; R-HSA-2562564; R-HSA-211651; R-HSA-201611; R-HSA-448703; R-HSA-114259; R-HSA-5681987; R-HSA-9694732; R-HSA-9694338; R-HSA-418852; R-HSA-3465448; R-HSA-9694377; R-HSA-9684336; R-HSA-9729741; R-HSA-201603; R-HSA-351877; R-HSA-351876; R-HSA-202939; R-HSA-201608; R-HSA-9686088; R-HSA-351913; R-HSA-201640; R-HSA-9693929; R-HSA-139898; R-HSA-351871; R-HSA-264871; R-HSA-6814387; R-HSA-1678981