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aspartic-type endopeptidase activity

Term Information

Accession
GO:0004190
Name
aspartic-type endopeptidase activity
Ontology
molecular_function
Synonyms
aspartic endopeptidase activity, aspartate protease activity, aspartic protease activity, aspartyl protease activity, carboxyl protease activity
Alternate IDs
None
Definition
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile. Source: ISBN:0198506732
Comment
None
History
See term history for GO:0004190 at QuickGO
Subset
None
Feedback
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Parents of aspartic-type endopeptidase activity (GO:0004190)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
aspartic-type endopeptidase activity [is_a relation] is_a  endopeptidase activity (GO:0004175)
aspartic-type endopeptidase activity [is_a relation] is_a  aspartic-type peptidase activity (GO:0070001)
Children of aspartic-type endopeptidase activity (GO:0004190)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process (GO:1902944) [is_a relation] is_a  aspartic-type endopeptidase activity
aspartic endopeptidase activity, intramembrane cleaving (GO:0042500) [is_a relation] is_a  aspartic-type endopeptidase activity