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aconitate hydratase activity

Term Information

Accession
GO:0003994
Name
aconitate hydratase activity
Ontology
molecular_function
Synonyms
aconitase activity, cis-aconitase activity, citrate(isocitrate) hydro-lyase (cis-aconitate-forming), citrate(isocitrate) hydro-lyase activity, citrate hydro-lyase activity
Alternate IDs
None
Definition
Catalysis of the reaction: citrate = isocitrate. The reaction occurs in two steps: (1) citrate = cis-aconitate + H2O, (2) cis-aconitate + H2O = isocitrate. This reaction is the interconversion of citrate and isocitrate via the labile, enzyme-bound intermediate cis-aconitate. Water is removed from one part of the citrate molecule and added back to a different atom to form isocitrate. Source: GOC:vw, GOC:pde, EC:4.2.1.3
Comment
This is a process composed of two reactions represented by the terms 'GO:0052632 : citrate hydro-lyase (cis-aconitate-forming) activity' and 'GO:0052633 : isocitrate hydro-lyase (cis-aconitate-forming) activity'.
History
See term history for GO:0003994 at QuickGO
Subset
None
Feedback
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Parents of aconitate hydratase activity (GO:0003994)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
aconitate hydratase activity [is_a relation] is_a  hydro-lyase activity (GO:0016836)
Children of aconitate hydratase activity (GO:0003994)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
regulation of aconitate hydratase activity (GO:1904232) [RO:0002211 relation] RO:0002211  aconitate hydratase activity
negative regulation of aconitate hydratase activity (GO:1904233) [RO:0002212 relation] RO:0002212  aconitate hydratase activity
positive regulation of aconitate hydratase activity (GO:1904234) [RO:0002213 relation] RO:0002213  aconitate hydratase activity
citrate dehydratase activity (GO:0047780) [BFO:0000051 relation] BFO:0000051  aconitate hydratase activity
isocitrate hydro-lyase (cis-aconitate-forming) activity (GO:0052633) [BFO:0000051 relation] BFO:0000051  aconitate hydratase activity