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DNA topoisomerase type I (single strand cut, ATP-independent) activity
Term Information
Accession
GO:0003917
Name
DNA topoisomerase type I (single strand cut, ATP-independent) activity
Ontology
molecular_function
Synonyms
type I DNA topoisomerase activity, type I topoisomerase activity, nicking-closing enzyme activity, omega-protein activity, relaxing enzyme activity, swivelase activity, untwisting enzyme activity, DNA topoisomerase I activity, deoxyribonucleate topoisomerase, topoisomerase
Alternate IDs
None
Definition
Catalysis of a DNA topological transformation by transiently cleaving one DNA strand at a time to allow passage of another strand; changes the linking number by +1 per catalytic cycle.
Source:PMID:8811192
Comment
Note that a further distinction, between type IA and type IB topoisomerases, is based on sequence or structural similarity between gene products that possess type I catalytic activity.
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