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Term Information

Accession
GO:0003905
Name
alkylbase DNA N-glycosylase activity
Ontology
molecular_function
Synonyms
DNA-3-methyladenine glycosidase II activity, alkylbase DNA glycosidase activity, 3-methyladenine DNA glycosylase II, AlkA, DNA glycosidase II activity, DNA-3-methyladenine glycosylase II, deoxyribonucleate 3-methyladenine glycosidase II, alkylated-DNA glycohydrolase (releasing methyladenine and methylguanine)
Alternate IDs
GO:0004036
Definition
Catalysis of the reaction: DNA with alkylated base + H2O = DNA with abasic site + alkylated base. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar to remove an alkylated base, leaving an apyrimidinic or apurinic site. Source: PMID:9224623, PMID:10872450, EC:3.2.2.21, GOC:elh
Comment
None
History
See term history for GO:0003905 at QuickGO
Subset
None
Feedback
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Parents of alkylbase DNA N-glycosylase activity (GO:0003905)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
alkylbase DNA N-glycosylase activity [is_a relation] is_a  DNA N-glycosylase activity (GO:0019104)
Children of alkylbase DNA N-glycosylase activity (GO:0003905)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
DNA-5-methylcytosine glycosylase activity (GO:1990053) [is_a relation] is_a  alkylbase DNA N-glycosylase activity
DNA-7-methyladenine glycosylase activity (GO:0052821) [is_a relation] is_a  alkylbase DNA N-glycosylase activity
DNA-7-methylguanine glycosylase activity (GO:0043916) [is_a relation] is_a  alkylbase DNA N-glycosylase activity
DNA-1,N6-ethenoadenine N-glycosylase activity (GO:0052820) [is_a relation] is_a  alkylbase DNA N-glycosylase activity
DNA-3-methylbase glycosylase activity (GO:0043733) [is_a relation] is_a  alkylbase DNA N-glycosylase activity
EC
3.2.2.21
MetaCyc
3.2.2.21-RXN