Planteome: Term Details for "transcription coregulator activity" (GO:0003712)

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Term Information

Accession: GO:0003712
Name: transcription coregulator activity
Ontology: molecular_function
Synonyms: transcription cofactor activity, transcriptional co-regulator, RNA polymerase II transcriptional cofactor activity
Alternate IDs: GO:0001104, GO:0016455
Definition: A transcription regulator activity that modulates the transcription of specific gene sets via binding to a DNA-bound DNA-binding transcription factor, either on its own or as part of a complex. Coregulators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators. Source: GOC:txnOH-2018, PMID:10213677, PMID:16858867, Wikipedia:Transcription_coregulator, PMID:24203923, PMID:25957681
Comment: Usage guidance: Most transcription coregulators do not bind DNA. Those that do usually bind DNA either in a non-specific or non-direct manner. If a protein binds DNA specifically, consider annotating to GO:0003700 DNA binding transcription factor activity.
History: See term history for GO:0003712 at QuickGO
Subset: goslim_drosophila
Related: Link to all annotated objects annotated to transcription coregulator activity.; Link to all direct and indirect annotations to transcription coregulator activity.; Link to all direct and indirect annotations download (limited to first 10,000) for transcription coregulator activity.
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BFO:0000001 entity
BFO:0000003 occurrent
BFO:0000015 process
GO:0008150 biological_process
GO:0009987 cellular process
GO:0008152 metabolic process
GO:0044237 cellular metabolic process
GO:0006807 nitrogen compound metabolic process
GO:0071704 organic substance metabolic process
GO:0009058 biosynthetic process
GO:0006725 cellular aromatic compound metabolic process
GO:0034641 cellular nitrogen compound metabolic process
GO:0046483 heterocycle metabolic process
GO:1901360 organic cyclic compound metabolic process
GO:0044238 primary metabolic process
GO:0044249 cellular biosynthetic process
GO:0043170 macromolecule metabolic process
GO:0006139 nucleobase-containing compound metabolic process
GO:1901576 organic substance biosynthetic process
GO:0019438 aromatic compound biosynthetic process
GO:0044271 cellular nitrogen compound biosynthetic process
GO:0018130 heterocycle biosynthetic process
GO:0090304 nucleic acid metabolic process
GO:1901362 organic cyclic compound biosynthetic process
GO:0009059 macromolecule biosynthetic process
GO:0034654 nucleobase-containing compound biosynthetic process
GO:0016070 RNA metabolic process
GO:0032774 RNA biosynthetic process
GO:0006351 DNA-templated transcription
GO:0003674 molecular_function
GO:0140110 transcription regulator activity
GO:0003712 transcription coregulator activity
GO:0003713 transcription coactivator activity
GO:0003714 transcription corepressor activity

Parents of transcription coregulator activity (GO:0003712)

subject	relation	object
transcription coregulator activity	is_a	transcription regulator activity (GO:0140110)

Children of transcription coregulator activity (GO:0003712)

subject	relation	object
transcription corepressor activity (GO:0003714)	is_a	transcription coregulator activity
transcription coactivator activity (GO:0003713)	is_a	transcription coregulator activity

transcription coregulator activity

Term Information

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Parents of transcription coregulator activity (GO:0003712)

Children of transcription coregulator activity (GO:0003712)

None.