Planteome: Term Details for "DNA-binding transcription factor activity" (GO:0003700)

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Term Information

Accession: GO:0003700
Name: DNA-binding transcription factor activity
Ontology: molecular_function
Synonyms: DNA binding transcription factor activity, gene-specific transcription factor activity, sequence-specific DNA binding transcription factor activity, bacterial-type DNA binding transcription factor activity, bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding transcription factor activity, bacterial-type RNA polymerase transcription enhancer sequence-specific DNA binding transcription factor activity, bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding, bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding, metal ion regulated sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding transcription factor activity, sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity, transcription factor activity, bacterial-type RNA polymerase core promoter proximal region sequence-specific binding, transcription factor activity, bacterial-type RNA polymerase proximal promoter sequence-specific DNA binding, transcription factor activity, bacterial-type RNA polymerase transcription enhancer sequence-specific binding, transcription factor activity, metal ion regulated sequence-specific DNA binding, nucleic acid binding transcription factor activity, transcription factor activity
Alternate IDs: GO:0001071, GO:0001204, GO:0001199, GO:0001131, GO:0000130, GO:0001151, GO:0001130
Definition: A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. Source: GOC:txnOH-2018
Comment: Usage guidance: Most DNA-binding transcription factors do not have enzymatic activity. The presence of specific DNA-binding domains known to be present in DNA-binding transcription factors (HOX, GATA etc) should be used to help decide whether a protein is a DNA binding transcription factor or a coregulator. If a protein has an enzymatic activity (for example, ubiquitin ligase, histone acetyl transferase) and no known DNA binding domain, consider annotating to GO:0003712 transcription coregulator activity. Special care should be taken with proteins containing zinc fingers, Myb/SANT and ARID domains, since only a subset of proteins containing these domains directly and selectively bind to regulatory DNA motifs in cis-regulatory regions.
History: See term history for GO:0003700 at QuickGO
Subset: goslim_metagenomics; goslim_chembl; goslim_drosophila; goslim_plant; goslim_mouse; goslim_agr; goslim_candida; goslim_yeast
Related: Link to all annotated objects annotated to DNA-binding transcription factor activity.; Link to all direct and indirect annotations to DNA-binding transcription factor activity.; Link to all direct and indirect annotations download (limited to first 10,000) for DNA-binding transcription factor activity.
Feedback: Contact the Planteome feedback if you find mistakes or have concerns about the data you find here.
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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BFO:0000001 entity
BFO:0000003 occurrent
BFO:0000015 process
GO:0008150 biological_process
GO:0009987 cellular process
GO:0008152 metabolic process
GO:0065007 biological regulation
GO:0044237 cellular metabolic process
GO:0006807 nitrogen compound metabolic process
GO:0071704 organic substance metabolic process
GO:0009058 biosynthetic process
GO:0006725 cellular aromatic compound metabolic process
GO:0034641 cellular nitrogen compound metabolic process
GO:0046483 heterocycle metabolic process
GO:1901360 organic cyclic compound metabolic process
GO:0044238 primary metabolic process
GO:0050789 regulation of biological process
GO:0044249 cellular biosynthetic process
GO:0043170 macromolecule metabolic process
GO:0006139 nucleobase-containing compound metabolic process
GO:1901576 organic substance biosynthetic process
GO:0050794 regulation of cellular process
GO:0019222 regulation of metabolic process
GO:0019438 aromatic compound biosynthetic process
GO:0044271 cellular nitrogen compound biosynthetic process
GO:0018130 heterocycle biosynthetic process
GO:0090304 nucleic acid metabolic process
GO:1901362 organic cyclic compound biosynthetic process
GO:0031323 regulation of cellular metabolic process
GO:0051171 regulation of nitrogen compound metabolic process
GO:0080090 regulation of primary metabolic process
GO:0009059 macromolecule biosynthetic process
GO:0034654 nucleobase-containing compound biosynthetic process
GO:0009889 regulation of biosynthetic process
GO:0060255 regulation of macromolecule metabolic process
GO:0019219 regulation of nucleobase-containing compound metabolic process
GO:0016070 RNA metabolic process
GO:0010467 gene expression
GO:0031326 regulation of cellular biosynthetic process
GO:0010556 regulation of macromolecule biosynthetic process
GO:0051252 regulation of RNA metabolic process
GO:0032774 RNA biosynthetic process
GO:0006351 DNA-templated transcription
GO:0003674 molecular_function
GO:0010468 regulation of gene expression
GO:2001141 regulation of RNA biosynthetic process
GO:0006355 regulation of DNA-templated transcription
GO:0140110 transcription regulator activity
GO:0003700 DNA-binding transcription factor activity
GO:0001216 DNA-binding transcription activator activity
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001217 DNA-binding transcription repressor activity
GO:0098531 ligand-activated transcription factor activity
GO:0043433 negative regulation of DNA-binding transcription factor activity
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0051090 regulation of DNA-binding transcription factor activity
GO:0016987 sigma factor activity

Parents of DNA-binding transcription factor activity (GO:0003700)

subject	relation	object
DNA-binding transcription factor activity	is_a	transcription regulator activity (GO:0140110)
DNA-binding transcription factor activity	BFO:0000050	regulation of DNA-templated transcription (GO:0006355)
DNA-binding transcription factor activity	BFO:0000051	transcription cis-regulatory region binding (GO:0000976)

Children of DNA-binding transcription factor activity (GO:0003700)

subject	relation	object
DNA-binding transcription factor activity, RNA polymerase II-specific (GO:0000981)	is_a	DNA-binding transcription factor activity
ligand-activated transcription factor activity (GO:0098531)	is_a	DNA-binding transcription factor activity
negative regulation of DNA-binding transcription factor activity (GO:0043433)	RO:0002212	DNA-binding transcription factor activity
DNA-binding transcription repressor activity (GO:0001217)	is_a	DNA-binding transcription factor activity
regulation of DNA-binding transcription factor activity (GO:0051090)	RO:0002211	DNA-binding transcription factor activity
DNA-binding transcription activator activity (GO:0001216)	is_a	DNA-binding transcription factor activity
positive regulation of DNA-binding transcription factor activity (GO:0051091)	RO:0002213	DNA-binding transcription factor activity
sigma factor activity (GO:0016987)	is_a	DNA-binding transcription factor activity

DNA-binding transcription factor activity

Term Information

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Parents of DNA-binding transcription factor activity (GO:0003700)

Children of DNA-binding transcription factor activity (GO:0003700)

None.