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granuloma formation

Term Information

Accession
GO:0002432
Name
granuloma formation
Ontology
biological_process
Synonyms
None
Alternate IDs
None
Definition
The formation of nodular inflammatory lesions, usually small or granular, firm, persistent, well-structured, and containing compactly grouped T lymphocytes and modified phagocytes such as epithelioid cells, giant cells, and other macrophages. Granuloma formation represents a chronic inflammatory response initiated by various infectious and noninfectious agents. The center of a granuloma consists of fused macrophages, which can become necrotic. Source: GOC:add, GO_REF:0000022, ISBN:068340007X, ISBN:0721601464, ISBN:081533642X
Comment
None
History
See term history for GO:0002432 at QuickGO
Subset
None
Feedback
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Parents of granuloma formation (GO:0002432)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
granuloma formation [BFO:0000050 relation] BFO:0000050  chronic inflammatory response (GO:0002544)
granuloma formation [is_a relation] is_a  immune effector process (GO:0002252)
Children of granuloma formation (GO:0002432)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of granuloma formation (GO:0002632) [RO:0002212 relation] RO:0002212  granuloma formation
regulation of granuloma formation (GO:0002631) [RO:0002211 relation] RO:0002211  granuloma formation
positive regulation of granuloma formation (GO:0002633) [RO:0002213 relation] RO:0002213  granuloma formation
None.