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transitional two stage B cell differentiation
Term Information
Accession
GO:0002334
Name
transitional two stage B cell differentiation
Ontology
biological_process
Synonyms
T2 stage B cell differentiation, transitional two stage B lymphocyte differentiation, transitional two stage B-cell differentiation, transitional two stage B-lymphocyte differentiation, transitional two stage B cell development
Alternate IDs
None
Definition
The process in which immature B cells from the bone marrow acquire the specialized features of T2 stage B cells in the spleen. T2 stage B cells express CD23 but not CD21.
Source:ISBN:0781735149,
GOC:jal
Comment
Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
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