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Term Information

Accession
GO:0002329
Name
pre-B cell differentiation
Ontology
biological_process
Synonyms
pre-B lymphocyte differentiation, pre-B cell development
Alternate IDs
None
Definition
The process in which a precursor cell type acquires the specialized features of a pre-B cell. Pre-B cells follow the pro-B cell stage of immature B cell differentiation and undergo rearrangement of heavy chain V, D, and J gene segments. Source: ISBN:0781735149, GOC:jal
Comment
Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
History
See term history for GO:0002329 at QuickGO
Subset
None
Feedback
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Parents of pre-B cell differentiation (GO:0002329)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
pre-B cell differentiation [is_a relation] is_a  immature B cell differentiation (GO:0002327)
Children of pre-B cell differentiation (GO:0002329)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
pre-B cell allelic exclusion (GO:0002331) [BFO:0000050 relation] BFO:0000050  pre-B cell differentiation
pre-B cell receptor expression (GO:0002330) [BFO:0000050 relation] BFO:0000050  pre-B cell differentiation
None.