You are using the Cyverse mirror of the Planteome Ontology Browser. The main site is currently down for maintenance.

Term Information

Accession
GO:0002315
Name
marginal zone B cell differentiation
Ontology
biological_process
Synonyms
marginal zone B lymphocyte differentiation, marginal zone B-cell differentiation, marginal zone B-lymphocyte differentiation, marginal zone B cell development
Alternate IDs
None
Definition
The process in which a B cell in the spleen acquires the specialized features of a marginal zone B cell. Marginal zone B cells are localized in a distinct anatomical region of the spleen that represents the major antigen-filtering and scavenging area (by specialized macrophages resident there). It appears that they are preselected to express a BCR repertoire similar to B-1 B cells, biased toward bacterial cell wall constituents and senescent self-components (such as oxidized LDL). Source: ISBN:0781735149, GOC:jal
Comment
Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
History
See term history for GO:0002315 at QuickGO
Subset
None
Feedback
Contact the Planteome feedback if you find mistakes or have concerns about the data you find here.
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

Filter results

Loading...
pending...
Parents of marginal zone B cell differentiation (GO:0002315)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
marginal zone B cell differentiation [is_a relation] is_a  mature B cell differentiation involved in immune response (GO:0002313)

This term has no children.

None.