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Term Information

Accession
GO:0002191
Name
cap-dependent translational initiation
Ontology
biological_process
Synonyms
None
Alternate IDs
None
Definition
The process where the cap structure, composed of a 7- methylguanosine (m7G) group and associated cap-binding proteins, located at the 5' end of an mRNA molecule, which serves as a molecular tag that marks the spot where the 40S ribosomal subunit, is recruited and will then scan in a 5' to 3' direction until an AUG codon is encountered in an appropriate sequence context to initiate mRNA translation. Source: PMID:19604130, PMID:17284590
Comment
None
History
See term history for GO:0002191 at QuickGO
Subset
None
Feedback
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Parents of cap-dependent translational initiation (GO:0002191)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
cap-dependent translational initiation [is_a relation] is_a  cytoplasmic translational initiation (GO:0002183)
Children of cap-dependent translational initiation (GO:0002191)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
positive regulation of cap-dependent translational initiation (GO:1903676) [RO:0002213 relation] RO:0002213  cap-dependent translational initiation
regulation of cap-dependent translational initiation (GO:1903674) [RO:0002211 relation] RO:0002211  cap-dependent translational initiation
negative regulation of cap-dependent translational initiation (GO:1903675) [RO:0002212 relation] RO:0002212  cap-dependent translational initiation
None.