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Term Information

Accession
GO:0002169
Name
3-methylcrotonyl-CoA carboxylase complex, mitochondrial
Ontology
cellular_component
Synonyms
mitochondrial 3-methylcrotonyl-CoA carboxylase holoenzyme, mitochondrial MCCC complex, mitochondrial methylcrotonoyl-CoA carboxylase complex
Alternate IDs
None
Definition
A mitochondrial protein complex which is capable of 3-methylcrotonyl-CoA carboxylase activity. In mammals, at least, consists as a dodecamer of 6 alpha and 6 beta subunits. MCCC-alpha has a covalently bound biotin essential for the ATP-dependent carboxylation. MCCC-beta possesses carboxyltransferase activity which presumably is essential for binding to 3-methylcrotonyl-CoA. Source: PMID:22869039, PMID:15868465, GOC:bf, GOC:hjd, PMID:17360195
Comment
None
History
See term history for GO:0002169 at QuickGO
Subset
None
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Parents of 3-methylcrotonyl-CoA carboxylase complex, mitochondrial (GO:0002169)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
3-methylcrotonyl-CoA carboxylase complex, mitochondrial [is_a relation] is_a  mitochondrial protein-containing complex (GO:0098798)
3-methylcrotonyl-CoA carboxylase complex, mitochondrial [is_a relation] is_a  methylcrotonoyl-CoA carboxylase complex (GO:1905202)

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None.