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Term Information

Accession
GO:0001788
Name
antibody-dependent cellular cytotoxicity
Ontology
biological_process
Synonyms
ADCC, antibody dependent cell death, antibody dependent cell killing, antibody-dependent cell death, antibody-dependent cell killing, type VI hypersensitivity
Alternate IDs
None
Definition
Cytolysis of target cells by natural killer cells, eosinophils, neutrophils, monocytes, or macrophages following engagement of antibodies bound to the target cells by Fc receptors on the effector cells. Source: PMID:9581795, GOC:pr, ISBN:0781735149, PMID:11677095
Comment
None
History
See term history for GO:0001788 at QuickGO
Subset
None
Feedback
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Parents of antibody-dependent cellular cytotoxicity (GO:0001788)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
antibody-dependent cellular cytotoxicity [is_a relation] is_a  type IIa hypersensitivity (GO:0001794)
antibody-dependent cellular cytotoxicity [is_a relation] is_a  leukocyte mediated cytotoxicity (GO:0001909)
Children of antibody-dependent cellular cytotoxicity (GO:0001788)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of antibody-dependent cellular cytotoxicity (GO:0001814) [RO:0002212 relation] RO:0002212  antibody-dependent cellular cytotoxicity
positive regulation of antibody-dependent cellular cytotoxicity (GO:0001815) [RO:0002213 relation] RO:0002213  antibody-dependent cellular cytotoxicity
regulation of antibody-dependent cellular cytotoxicity (GO:0001813) [RO:0002211 relation] RO:0002211  antibody-dependent cellular cytotoxicity