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immunological synapse
Term Information
Accession
GO:0001772
Name
immunological synapse
Ontology
cellular_component
Synonyms
supramolecular activation cluster, c-SMAC
Alternate IDs
None
Definition
An area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell formed through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and the target cell and facilitating activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction.
Source:PMID:11244041,
GOC:mgi_curators,
PMID:11376300
Link
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Link
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Link
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for immunological synapse.
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