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fatty acid alpha-oxidation
Term Information
Accession
GO:0001561
Name
fatty acid alpha-oxidation
Ontology
biological_process
Synonyms
None
Alternate IDs
None
Definition
A metabolic pathway by which 3-methyl branched fatty acids are degraded. These compounds are not degraded by the normal peroxisomal beta-oxidation pathway, because the 3-methyl blocks the dehydrogenation of the hydroxyl group by hydroxyacyl-CoA dehydrogenase. The 3-methyl branched fatty acid is converted in several steps to pristenic acid, which can then feed into the beta-oxidative pathway.
Source:PMID:10198260
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