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Term Information

Accession
GO:0001534
Name
radial spoke
Ontology
cellular_component
Synonyms
None
Alternate IDs
None
Definition
Protein complex that links the outer microtubule doublet of a 9+2 type ciliary or flagellar axoneme with the sheath that surrounds the central pair of microtubules. Composed of a stalk that attaches to each doublet microtubule and a globular structure (spoke head) that projects toward the central pair of microtubules. Source: PMID:9450971, GOC:krc, PMID:22118931, ISBN:0124325653, PMID:34871179, PMID:25694453
Comment
Radial spokes are involved in some types of beating motions of the cilium. The radial spoke is usually a T-shaped structure comprised of a short base that attaches to the A-microtubule of an axonemal outer microtubule doublet (MTD) of a cilium, an elongated stalk, a neck complex, and an orthogonal head structure that extends perpendicularly towards the inner sheath and the central pair (CP) microtubules. Groups of radial spokes (RSs) repeat along the MTD with regular spacing. In most organisms, each group of radial spokes is comprised of a triplet of spokes: RS1, RS2, and RS3. In some organisms (e.g. Chlamydomonas and Sarcophaga bullata), each group contains a doublet of radial spokes: RS1 and RS2, while RS3 is represented only as a stump (referred to as RS3S) attached to the A-microtubule but lacking the rest of the stalk structure and entirely lacking the head structure.
History
See term history for GO:0001534 at QuickGO
Subset
goslim_pir
Feedback
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Parents of radial spoke (GO:0001534)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
radial spoke [is_a relation] is_a  protein-containing complex (GO:0032991)
radial spoke [BFO:0000050 relation] BFO:0000050  axoneme (GO:0005930)
Children of radial spoke (GO:0001534)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
radial spoke 1 (GO:0120333) [is_a relation] is_a  radial spoke
radial spoke base (GO:0120339) [BFO:0000050 relation] BFO:0000050  radial spoke
9+2 motile cilium (GO:0097729) [BFO:0000051 relation] BFO:0000051  radial spoke
kinocilium (GO:0060091) [BFO:0000051 relation] BFO:0000051  radial spoke
radial spoke stalk (GO:0001536) [BFO:0000050 relation] BFO:0000050  radial spoke
radial spoke head (GO:0001535) [BFO:0000050 relation] BFO:0000050  radial spoke
radial spoke neck (GO:0120343) [BFO:0000050 relation] BFO:0000050  radial spoke
radial spoke 3 (GO:0120335) [is_a relation] is_a  radial spoke
radial spoke 2 (GO:0120334) [is_a relation] is_a  radial spoke
Wikipedia
Radial_spoke