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Term Information

Accession
GO:0000977
Name
RNA polymerase II transcription regulatory region sequence-specific DNA binding
Ontology
molecular_function
Synonyms
RNA polymerase II regulatory region DNA binding
Alternate IDs
GO:0001012
Definition
Binding to a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II. Source: GOC:txnOH
Comment
To minimize ambiguity in the use of the word "promoter" in GO, we have chosen the phrase "transcription regulatory region" to refer to all of the regulatory regions. Regulatory regions in the DNA which control initiation may include the "core promoter" where the basal transcription machinery binds, the "core promoter proximal region" where regulatory factors other than the basal machinery bind. There are also additional regulatory regions, in both the DNA and the RNA transcript, which regulate elongation or termination of transcription.
History
See term history for GO:0000977 at QuickGO
Subset
None
Feedback
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Parents of RNA polymerase II transcription regulatory region sequence-specific DNA binding (GO:0000977)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
RNA polymerase II transcription regulatory region sequence-specific DNA binding [is_a relation] is_a  transcription cis-regulatory region binding (GO:0000976)
Children of RNA polymerase II transcription regulatory region sequence-specific DNA binding (GO:0000977)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
RNA polymerase II cis-regulatory region sequence-specific DNA binding (GO:0000978) [is_a relation] is_a  RNA polymerase II transcription regulatory region sequence-specific DNA binding
DNA-binding transcription factor activity, RNA polymerase II-specific (GO:0000981) [BFO:0000051 relation] BFO:0000051  RNA polymerase II transcription regulatory region sequence-specific DNA binding
regulation of RNA polymerase II regulatory region sequence-specific DNA binding (GO:1903025) [RO:0002211 relation] RO:0002211  RNA polymerase II transcription regulatory region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding (GO:0000979) [is_a relation] is_a  RNA polymerase II transcription regulatory region sequence-specific DNA binding
positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding (GO:1905636) [RO:0002213 relation] RO:0002213  RNA polymerase II transcription regulatory region sequence-specific DNA binding
negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding (GO:1903026) [RO:0002212 relation] RO:0002212  RNA polymerase II transcription regulatory region sequence-specific DNA binding
RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding (GO:0001162) [is_a relation] is_a  RNA polymerase II transcription regulatory region sequence-specific DNA binding
None.