Planteome: Term Details for "oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity" (GO:0000703)

Term Information

Accession: GO:0000703
Name: oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity
Ontology: molecular_function
Synonyms: oxidized pyrimidine base lesion DNA N-glycosylase activity, endodeoxyribonuclease III, endonuclease III, endonuclease VIII activity, pyrimidine-specific oxidized base lesion DNA N-glycosylase activity, DNA glycosylase/AP-lyase, DNA glycosylase/beta-lyase, bifunctional DNA glycosylase
Alternate IDs: GO:0019004
Definition: Catalysis of the removal oxidized pyrimidine bases by cleaving the N-C1' glycosidic bond between the oxidized pyrimidine and the deoxyribose sugar. The reaction involves formation of a covalent enzyme-pyrimidine base intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apyrimidinic (AP) site. Source: PMID:11554296, GOC:elh
Comment: Consider also annotating to the molecular function term 'DNA-(apurinic or apyrimidinic site) lyase activity ; GO:0003906'.
History: See term history for GO:0000703 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity.; Link to all direct and indirect annotations to oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity.; Link to all direct and indirect annotations download (limited to first 10,000) for oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity.
Feedback: Contact the Planteome feedback if you find mistakes or have concerns about the data you find here.
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

Filter results

Viewing options

BFO:0000001 entity
BFO:0000003 occurrent
BFO:0000015 process
GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016787 hydrolase activity
GO:0140640 catalytic activity, acting on a nucleic acid
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0140097 catalytic activity, acting on DNA
GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds
GO:0019104 DNA N-glycosylase activity
GO:0000702 oxidized base lesion DNA N-glycosylase activity
GO:0000703 oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity
GO:0034042 5-formyluracil DNA N-glycosylase activity
GO:0034043 5-hydroxymethyluracil DNA N-glycosylase activity

Parents of oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity (GO:0000703)

subject	relation	object
oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity	is_a	oxidized base lesion DNA N-glycosylase activity (GO:0000702)

Children of oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity (GO:0000703)

subject	relation	object
5-hydroxymethyluracil DNA N-glycosylase activity (GO:0034043)	is_a	oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity
5-formyluracil DNA N-glycosylase activity (GO:0034042)	is_a	oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity

Reactome: R-HSA-110227; R-HSA-110226; R-HSA-110224