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Term Information

Accession
GO:0000354
Name
cis assembly of pre-catalytic spliceosome
Ontology
biological_process
Synonyms
cis assembly of U12-type pre-catalytic spliceosome, cis assembly of U2-type pre-catalytic spliceosome, formation of spliceosomal A2-1 complex, formation of spliceosomal B1 complex, spliceosomal A2-1 complex biosynthesis, spliceosomal A2-1 complex formation, spliceosomal B1 complex biosynthesis, spliceosomal B1 complex formation
Alternate IDs
GO:0000361, GO:0000360
Definition
Assembly of a spliceosomal complex containing the intact pre-mRNA and all of the spliceosomal snRNPs. This occurs when the tri-snRNP associates with the pre-mRNA and associated snRNPs in an ATP-dependent manner. Source: GOC:krc, GOC:mtg_mpo, ISBN:0879695897
Comment
Note that this step represents formation of the A2-1 complex (yeast) or the B1 complex (mammals).
History
See term history for GO:0000354 at QuickGO
Subset
None
Feedback
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Parents of cis assembly of pre-catalytic spliceosome (GO:0000354)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
cis assembly of pre-catalytic spliceosome [is_a relation] is_a  protein-RNA complex assembly (GO:0022618)
cis assembly of pre-catalytic spliceosome [BFO:0000050 relation] BFO:0000050  mRNA cis splicing, via spliceosome (GO:0045292)
cis assembly of pre-catalytic spliceosome [BFO:0000050 relation] BFO:0000050  spliceosomal complex assembly (GO:0000245)

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